Heres what you need to know about alcohol and blood pressure including how alcohol can interact with your blood pressure medications. The Swedish Multicentre Group. URL of this page: https://medlineplus.gov/druginfo/meds/a682348.html. We asked 34 people what they think about isosorbide mononitrate (Monoket): Get Isosorbide mononitrate (Monoket) for as low as $29.86, 180 tablets of isosorbide mononitrate 10mg. Talk to your doctor about the possible risks of using this medication for your condition. The effects of this exposure on a nursing infant are unknown. It is used to treat and prevent a wide range of different conditions. These relax smooth muscle within the blood vessels, widening them and making it easier for blood and oxygen to reach the heart Calcium antagonists (eg, diltiazem, nifedipine, nimodipine, verapamil). Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Longer-acting tablets and capsules are taken once daily in the morning. Dated October 2016. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. Accessed Sept. 7, 2022. 8.0 out of 10 from a total of Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. Is not subject to the Controlled Substances Act. Compare a few possible alternatives below. Making any changes without doctor's advice can be dangerous. Lyrica and Metoclopramide drug interaction, Calcitriol and Metoclopramide drug interaction. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. If you have an eye condition called glaucoma. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Otherwise, call a poison control center right away. If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. privacy practices. In: Current Medical Diagnosis & Treatment 2022. Federal government websites often end in .gov or .mil. View all Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Liperoti R, et al. If you become pregnant while taking isosorbide, call your doctor. Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Alcohol, including beer, wine, and spirits, does raise your blood pressure if its consumed in excess. Modified-release nitrate preparations: use a once-daily dose to maintain a nitrate-low period and thus minimize tolerance. Alcohol will increase the risk of you experiencing side-effects such as feeling dizzy and light-headed. What are the side effects of Isosorbide Mononitrate ? To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Isosorbide mononitrate is a nitrate-class drug used for the prophylactic treatment of angina pectoris; that is, it is taken in order to prevent or at least reduce the occurrence of angina. View more. Change positions slowly until your body is used to the medication. You may report side effects to the FDA at 1-800-FDA-1088. Take care, thanks. View more, Nitroglycerin dilates veins, relieving chest pain and lowering blood pressure. isosorbide mononitrate (Rx) Brand and Other Names: Imdur, Monoket, more. If you forget to take a dose, take it as soon as you remember. Advertising revenue supports our not-for-profit mission. Accessibility Do not store in the bathroom. This survey is being conducted by the WebMD marketing sciences department. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. This content does not have an English version. https://naturalmedicines.therapeuticresearch.com. What are the interactions of Isosorbide Mononitrate ? flushing - try to cut down on coffee, tea and alcohol because they can make flushing worse. 19 are major, 174 are moderate, and 2 are minor. This side-effect usually disappears after a few days, Do not drive and do not use tools or machines while affected, If either of these becomes troublesome, speak with your doctor. Does isosorbide mononitrate (Monoket) lower blood pressure? This site complies with the HONcode standard for trustworthy health information: verify here. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). HHS Vulnerability Disclosure, Help Some brands of isosorbide mononitrate tablets should be taken two or three times a day. This site complies with the HONcode standard for trustworthy health information: verify here. Isosorbide mononitrate: isosorbide mononitrate. Do not stop taking isosorbide without talking to your doctor. Never give it to other people even if their condition appears to be the same as yours. 2006 Apr;95(4):217-23. doi: 10.1007/s00392-006-0367-x. Methods: Be sure to mention any of the following: aspirin; beta blockers such as atenolol (Tenormin, Tenoretic), carteolol , labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, in Dutoprol, in Lopressor HCT), nadolol (Corgard, in Corzide), propranolol (Hemangeol, Inderal, Innopran), sotalol (Betapace, Sorine, Sotylize), and timolol; calcium channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), diltiazem (Cardizem, Cartia, Dilt-CD, others), felodipine (Plendil), isradipine, nifedipine (Adalat CC, Afeditab, Procardia), and verapamil (Calan, Covera, Verelan); ergot-type medications such as bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (D.H.E. Aspirin has an average rating of This medicine is available only with your doctor's . Please see a good cardiologist, get admitted, get checked thoroughly. To help you remember, take it at the same times each day. Higher dosages are associated with stomach irritation and Talk to your provider if you notice your chest pain starts to get worse. Isosorbide mononitrate should not be used in patients with severe anaemia, severe hypotension, closed angle glaucoma or severe hypovolaemia.Isosorbide mononitrate may give rise to postural hypotension and syncope in some patients. As precautionary measure, it is preferable to avoid the use of isosorbide mononitrate during pregnancy. Let your provider know if you are using any medications for erectile dysfunction before you start taking isosorbide mononitrate (Monoket). Alcohol or marijuana (cannabis) can make you more dizzy. Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as isosorbide dinitrate, nitroglycerin); or if you have any other allergies. If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. And as many as 25% of people also take medicines ordered for them by their health care providers, also called prescription medicines. 1998 Oct;61(10):577-83. You need to take it every day in order for it to work. My cardiologist recommended I get on metropolol. Nitrate-Induced Headache in Patients with Stable Angina Pectoris: Beneficial Effect of Starting on a Low Dosage. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Danshen can interact strongly with some heart medicines, such as: Evening primrose may raise your risk of bleeding if you also take a blood thinner, such as: Garlic may raise your risk of bleeding if you also take a blood thinner, such as: Ginkgo biloba may raise your risk of bleeding if you also take a blood thinner, such as: If you take ginseng with warfarin, it may lessen how well warfarin works. Pricing based on most commonly-filled versions: 180 tablets of isosorbide mononitrate 10mg. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Alternative cancer treatments: 11 options to consider. Take them to your local pharmacy which will dispose of them for you. The information on this page is written and peer reviewed by qualified clinicians. Last Revised - 09/15/2019. Anti-ischemic and anti-anginal effects of controlled-release and conventional isosorbide-5-mononitrate in stable angina pectoris. Once- versus twice-daily administration of controlled-release isosorbide-5-mononitrate 60 mg in the treatment of stable angina pectoris. B12 and folic acid is essential along with iron. Thirty percent of the patients never experienced headache from the given dosages. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Isosorbide is in a class of medications called vasodilators. It is not intended as medical advice for individual conditions or treatment. Mehta D. Botanical medicines. Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. Copyright 2023 IBM Watson Health. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Elantan, Imdur, Isotard, Monomax, Tardisc, Xismox. Accessed Sept. 7, 2022. May also be prescribed off label for Esophageal Spasm. The dose is according to the body weight and severity of the condition. Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. Copyright, 2023. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Isosorbide Mononitrate side effects by likelihood and severity. Are you looking for information on isosorbide dinitrate (Isordil) instead? Other side effects not listed may also occur in some patients. Isosorbide mononitrate belongs to the group of medicines called nitrates. Never take extra doses or stop taking it suddenly unless your provider tells you to do so. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. The short-acting tablet is usually taken as 10 mg to 40 mg by mouth 2 or 3 times daily with at least a 14 hour period of time per day where you don't take any doses. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. Watch for any symptoms that you may be having a drug interaction, such as: Mayo Clinic does not endorse companies or products. What side effects can this medication cause? Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. The longer you take isosorbide mononitrate, the more your body can become used to it (called tolerance), and then it can have less of an effect. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. Registered in England and Wales. Theyre fast, easy-to-use and free! Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. The tablet usually is taken two or three times daily. If you have any questions about this medicine ask your pharmacist. https://naturalmedicines.therapeuticresearch.com. Along with its needed effects, a medicine may cause some unwanted effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Which drugs or supplements interact with isosorbide mononitrate? Do not start, stop, or change the dosage of any medicines without your doctor's approval. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. 2017; doi:10.1016/j.jacc.2016.11.078. Some of these interactions can be life-threatening. In: Textbook of Natural Medicine. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. It can cause your blood pressure to become dangerously low. This content does not have an Arabic version. Isosorbide mononitrate helps to prevent angina chest pain from developing. Breastfeeding:There is data that nitrates are excreted in breast milk and may cause methemoglobinemia in infants. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. information is beneficial, we may combine your email and website usage information with Contact your doctor immediately if you experience any of the following: The following side effects may get better over time as your body gets used to the medication. Isosorbide tablets are also used with other medications to treat heart failure. In the US - Call your doctor for medical advice about side effects. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. Be sure to follow your provider's instructions about when to take isosorbide mononitrate (Monoket). This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. https://www.uptodate.com/contents/search. Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. Check with your doctor immediately if any of the following side effects occur: burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, fast, slow, irregular, pounding, or racing heartbeat or pulse, itching, pain, redness, or swelling on the leg, numbness or tingling in the hands, feet, or lips, pain or discomfort in the arms, jaw, back, or neck, pain, tension, and weakness upon walking that subsides during periods of rest, shakiness in the legs, arms, hands, or feet, swelling of the face, fingers, feet, or lower legs, trembling or shaking of the hands or feet, vomiting of blood or material that looks like coffee grounds, Bluish-colored lips, fingernails, or palms. It works more slowly and lasts for about 12 hours, so you only need to take it once a day. Take the missed dose as soon as you remember it. Using this medicine with any of the following medicines is not recommended. See also: aspirin side effects in more detail. The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. You can develop a tolerance to isosorbide mononitrate (Monoket) over time, which means the dose you've been taking doesn't work as well. Headache is often a sign that this medication is working. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. Some side effects may occur that usually do not need medical attention. Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. There are a number of medications that your doctor can prescribe in place of isosorbide mononitrate (Monoket). Accessed Sept. 7, 2022. Isosorbide may cause other side effects. Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. coma (loss of consciousness for a period of time). This should pass after a few days. This medication belongs to a class of drugs known as nitrates. Data were assessed for carryover and time effects. Portions of this document last updated: Feb. 01, 2023. Make sure laboratory personnel and all your doctors know you use this drug. Consult your doctor before breast-feeding. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. 46 ratings on Drugs.com. Lifestyle changes such as dietary changes, exercise, and not smoking may help this drug work better. Your doctor will prescribe you a short-acting nitrate for you to take if this happens. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Real test is coronary angiography. If concomitant therapy cannot be avoided, monitor clinical effects of the . If you experience any other symptoms which you think may be due to the medicine, please speak with your doctor or pharmacist for further advice. Sept. 26, 2022. All rights reserved. It might help to take isosorbide mononitrate and dinitrate after meals. Classes: Nitrates, Angina Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths tablet 10mg 20mg. Careers. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Then, there was a two-week placebo washout, after which the alternative treatment was given. Natural Medicines. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. 41% of reviewers reported a positive effect, while 50% reported a negative effect. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. An official website of the United States government. Isosorbide mononitrate has an average rating of Hawthorn. Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). Can cause dizziness, especially when you change positions, Interacts with erectile dysfunction medications. Isosorbide dinitrate (Isordil) is available as both a short-acting tablet and long-acting capsule. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Usually avoid combinations; use it only under special circumstances. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Herbal supplements are natural, so they must be safe, right? Things to remember when you fill your prescription. Many common herbal supplements interact with common heart medicines. Isosorbide mononitrate helps to prevent angina chest pain from developing. Is it safe to drive while on this medicine? Isosorbide mononitrate systemic 60 mg (A ID). As precautionary measure, breast-feeding should be discontinued during treatment with isosorbide mononitrate. My EKG showed Assess your symptoms online with our free symptom checker. WebMD does not provide medical advice, diagnosis or treatment. There are 195 drugs known to interact with I would rather take the chance of a heart attack than have no quality of life. Isosorbide mononitrate belongs to the group of medicines called nitrates. Reduction of blood-nitrate concentrations to low levels for 4 to 12 hours each day usually maintains effectiveness in such patients. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). Coenzyme Q-10 Natural Medicines. Try to keep your regular appointments with your doctor. The IR version can help treat and prevent angina. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. This is because the tablets/capsules are specially made to release the medicine they contain in a controlled way. Trapidil is as effective as isosorbide-dinitrate for treating stable angina pectoris: a multinational, multicenter, double-blind, randomized study. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Some products have ingredients that could worsen your heart failure. Contact your provider right away if you feel as if you are going to pass out and are experiencing an irregular heartbeat, nausea, vomiting, changes in vision, more sweating, or cold and clammy skin. you should know that you may experience headaches every day during your treatment with isosorbide. Cardizem may also be used for purposes not listed in this medication guide. It has a very short duration of action and may not be suitable for some people. Isosorbide mononitrate (Monoket) is a nitrate vasodilator.